| Sep 17, 2026 | Ra Capital Management, L.P. Director & 10% Owner | Sold | 3,448,811 | $6.33 | $21.84M | |
| Jul 7, 2026 | Peter A. Thompson Director | Sold | 85,918 | $44.86 | $3.85M | |
| Jul 7, 2026 | Orbimed Advisors LLC Director | Sold | 85,918 | $44.86 | $3.85M | |
| Jul 6, 2026 | Jennifer Fitzpatrick | Sold | 10,250 | $43.60 | $447K | |
| Jun 30, 2026 | Peter A. Thompson Director | Sold | 115,844 | $45.50 | $5.27M | |
| Jun 30, 2026 | Orbimed Advisors LLC Director | Sold | 115,844 | $45.50 | $5.27M | |
| May 27, 2026 | Peter A. Thompson Director | Sold | 101 | $44.49 | $4K | |
| May 27, 2026 | Orbimed Advisors LLC Director | Sold | 101 | $44.49 | $4K | |
| May 7, 2026 | Peter A. Thompson Director | Sold | 292,952 | $45.62 | $13.36M | |
| May 7, 2026 | Orbimed Advisors LLC Director | Sold | 292,952 | $45.62 | $13.36M | |
| Apr 17, 2026 | Peter A. Thompson Director | Sold | 55,345 | $44.67 | $2.47M | |
| Apr 17, 2026 | Orbimed Advisors LLC Director | Sold | 55,345 | $44.67 | $2.47M | |
| Apr 14, 2026 | Peter A. Thompson Director | Sold | 510,583 | $44.94 | $22.95M | |
| Apr 14, 2026 | Orbimed Advisors LLC Director | Sold | 510,583 | $44.94 | $22.95M | |
| Mar 5, 2026 | Jennifer Fitzpatrick | Sold | 10,250 | $33.86 | $347K | |
| Feb 2, 2026 | Peter A. Thompson Director | Sold | 30,953 | $44.58 | $1.38M | |
| Feb 2, 2026 | Orbimed Advisors LLC Director | Sold | 30,953 | $44.58 | $1.38M | |
| Jan 22, 2026 | Tpg Gp A, LLC 10% Owner | Sold | 250,000 | $40.00 | $10.00M | |
| Dec 24, 2025 | Orbimed Advisors LLC Director | Sold | 33,356 | $44.55 | $1.49M | |
| Dec 24, 2025 | Peter A. Thompson Director | Sold | 33,356 | $44.55 | $1.49M | |
| Dec 17, 2025 | Orbimed Advisors LLC Director | Sold | 1,875 | $44.49 | $83K | |
| Dec 17, 2025 | Peter A. Thompson Director | Sold | 1,875 | $44.49 | $83K | |
| Dec 5, 2025 | Jennifer Fitzpatrick | Sold | 10,250 | $40.52 | $415K | |
| Nov 24, 2025 | Orbimed Advisors LLC Director | Sold | 108,073 | $44.55 | $4.81M | |
| Nov 24, 2025 | Peter A. Thompson Director | Sold | 108,073 | $44.55 | $4.81M | |
| Nov 20, 2025 | Ra Capital Management, L.P. Director & 10% Owner | Sold | 30,316 | $39.61 | $1.20M | |
| Nov 17, 2025 | Ra Capital Management, L.P. Director & 10% Owner | Sold | 136,351 | $40.34 | $5.50M | |
| Oct 24, 2025 | Ra Capital Management, L.P. Director & 10% Owner | Sold | 373,610 | $39.51 | $14.76M | |
| Oct 21, 2025 | Michael Cloonan President & CEO | Sold | 99,800 | $36.26 | $3.62M | |
| Oct 21, 2025 | Bruce Booth Director | Sold | 88,878 | $34.22 | $3.04M | |
| Oct 16, 2025 | Bruce Booth Director | Sold | 286,369 | $32.30 | $9.25M | |
| Oct 15, 2025 | Michael Cloonan President & CEO | Sold | 25,200 | $31.28 | $788K | |
| Oct 10, 2025 | Bruce Booth Director | Sold | 194,932 | $30.47 | $5.94M | |
| Oct 3, 2025 | Bruce Booth Director | Sold | 49,546 | $29.99 | $1.49M | |
| Sep 29, 2025 | Bruce Booth Director | Sold | 78,693 | $30.08 | $2.37M | |
| Sep 26, 2025 | Michael Cloonan President & CEO | Sold | 25,000 | $29.11 | $728K | |
| Sep 4, 2025 | Jennifer Fitzpatrick | Sold | 10,250 | $23.12 | $237K | |
| Aug 29, 2025 | Elena Ridloff CFO | Sold | 9,584 | $25.09 | $240K | |
| Aug 26, 2025 | Michael Cloonan President & CEO | Sold | 25,000 | $24.97 | $624K | |
| Aug 26, 2025 | Elena Ridloff CFO | Sold | 23,416 | $25.70 | $602K | |
| Aug 20, 2025 | Michael Cloonan President & CEO | Sold | 25,000 | $22.75 | $569K | |
| Aug 19, 2025 | Elena Ridloff CFO | Sold | 52,000 | $21.62 | $1.12M | |
| Jun 27, 2025 | Tpg Gp A, LLC 10% Owner | Bought | 60,000 | $15.84 | $950K | |
| Feb 10, 2025 | Tpg Gp A, LLC 10% Owner | Bought | 1,125,000 | $18.00 | $20.25M | |
| Feb 10, 2025 | Ra Capital Management, L.P. Director & 10% Owner | Bought | 1,125,000 | $18.00 | $20.25M | |
| Feb 10, 2025 | Orbimed Advisors LLC Director | Bought | 550,000 | $18.00 | $9.90M | |
| Feb 10, 2025 | Peter A. Thompson Director | Bought | 550,000 | $18.00 | $9.90M | |
| Feb 10, 2025 | Bruce Booth Director | Bought | 60,000 | $18.00 | $1.08M | |
| Feb 10, 2025 | Atlas Venture Fund Xi, L.P. 10% Owner | Bought | 60,000 | $18.00 | $1.08M | |
